Msud

MSUD or maple syrup urine disease is a condition that has the potential to cause grave consequences due the manner in which it impinges on the body’s capacity of breaking down three kinds of amino acids namely leucine, isoleucine and valine. The three amino acids when not employed for building protein go through the process of recycling, breaking down and utilised for energy. BCKD or branched-chain alpha-ketoacid dehydrogenase is the team formed by the unison of six proteins that generally break down the three amino acids.

Individuals having MSUD possess a mutation that leads to a paucity of one of the six proteins which constitute the BCKD complex. Hence, their bodies are incapable of breaking down the three amino acids present in their blood stream leading to brisk deterioration of brain cells and fatality in case not treated.

Faults in one of the 6 subunits which constitute the BCKD protein complex could lead to MSUD surfacing. The prevailing flaw occurs due to a mutation in a gene present on chromosome number 19 which sets the alpha sub-element of the BCKD complex – BCKDHA.

MSUD is an autosomally recessive heritable condition wherein an infant would require inheriting a flawed reproduction of the gene from both the parents in order to get MSUD. In case both mother and father are carrying the MSUD gene, then all their kids would bear a twenty-five percent likelihood of developing the disorder and a fifty percent likelihood of being carriers of this disorder.

Symptoms of MSUD:

MSUD is present in a characteristic type and numerous less prevalent types. Each type appears to vary in how severe it is and its typical traits. Yet, all sub forms of the disorder could be due to mutations in any one of the six genes employed for building the BCKD protein complex.

  • A child having this disorder could seem normal subsequent to delivery. However, in 3-4 days time, the symptoms start appearing which comprise of diminished craving for foods, feeling fuzzy and sweet odour urine. The typical odour is the consequence of high levels of amino acids present in the urine due to which the disorder derived its name.
  • In case not treated, the situation generally deteriorates. The child would undergo seizure attacks, enter a state of coma and death could occur in the initial couple of months of its life.
Diagnosis & Tests:

In certain states, all the infants in a span of a day’s time after their delivery undergo screening for MSUD. Blood sample is drawn from the child’s heel for analysis of elevated levels of leucine.

Treatment of MSUD:
  • Treatment generally comprises of dietetic curbing of the three amino acids namely, leucine, isoleucine and valine which has to be commenced quite soon for averting damage to the brain.
  • Infants having the disorder are given a special fortified formulation that has no presence of the three amino acids.
  • Such children when they become adults have to be watchful of their dietetic intake for life long and steer clear from meat products, eggs and nuts.
  • In case elevated levels of the 3 amino acids are detected in the person, then intravenous administration of a solution could assist the body is using up the three amino acids for synthesising protein.
  • Gene therapy additionally appears to be the imminent cure for those having MSUD wherein substitution of the mutated gene with a normal replica facilitates the cells in generating a efficient BCKD protein complex and for breaking down the excessive amino acids.

MSUD is rarely found with one among 1, 80, 000 newly born having MSUD, though in certain populaces it is more prevalent.

All about Broca’s Aphasia

Aphasia is a condition where there is a great language impairment thus affecting not only the production but also the comprehension of speech. It also influences the ability to write or read. Aphasia is always invariably due a brain injury sometimes in the form of a stroke. It is especially seen to happen in the elders. Brain injuries resulting in a condition like aphasia also can be caused due to brain tumours, head trauma and also other infections.

In the year 1865, Paul Broca referred to patients who had a lack of speech ability and also those who had a hemiparesis and aid that this has been caused due to a damage in the language part of the brain. After the patient died and a post mortum examination was made, Broca showed how the entire portion of the left posterior frontal lobe in the operculum area had got affected. This discovery that Broca gave to the world brought about the idea that the brain had compartments and was also lateral. Cerebral localization thus became a very popular topic for all those interested.

Broca’s Aphasia is mainly dominated by a disability to speak, sentences and even few words. It has many pauses. The patient normally is seen to come with a great distorted effect and with a huge effort. The intonation is normally single pitched and is flat. So the speech is more telegraphic without any emotion. The words are repeated and the phrases are also impaired. But the comprehension of the aural regions for speech is totally intact. Normally a right hemiparesis is associated with this and it normally is localized to the leg, arm and the face.

Normally patients who are affected are seen to have lesions which cause Broca’s Aphasia and these are involved with the frontal operculaum and the motor regions and the premotor regions of the brain. These are found positioned in the portions of the brain that lie behind and are normally on top of the Broca area. There are also lesions that are found deep inside the white matter of the brain and also the basal ganglia. This is what results in Broca’s aphasia. Normally the more extensively the cerebrum is involved the lesser the prognosis is possible for recovery.

Aphasia is found to very severe sometimes and thus the communication for the patient is totally impossible. Sometimes the symptoms are very mild. Broca’s Aphasia is found to either affect the use of language, or the capacity to retrieve the names or the way one can put the words to sentences. It also affects the capacity to read. But mostly the other multiple parts of communication are affected. Some of the channels are seen to be inaccessible for some information.

The professionals dealing with the problem normally try to find out the exact function that is lacking and assess the treatment method as per their findings. They try to enhance the use of channels that are in hand.

Broca’s aphasia also called non fluent aphasia affect the speech output and is totally ruled by short utterances of the words. The vocabulary is also limited and the sound formations is very clumsy and also with great effort. Though the person understands speech easily he is not able to reproduce it as well. Thus this non fluent speech disability is because of the effort that is to be applied to speak. The left frontal lobe is one of the main areas of language in the cerebral cortex as it is the part that rules the motor aspect of the speech ability in an individual. So usually the patient is able to understand what words mean, but have trouble speaking. The other names for this disability are motor aphasia, expressive aphasia. Depending on how severe the condition, is, the Broca’s aphasia symptoms normally are either dysarthria where the person cannot comprehend and speak or it could through writing a complete loss of speaking aloud.

All the individuals who have Broca’s Aphasia were usually thought to have a lot of damage to the frontal lobe but more recent studies show that the patients with this problem have lesions to the medial insular cortex.

All in all it is a condition that has to be attended to and there are numerous ways this can be handled.

Alopecia Areata in Kids: How to Manage the Condition?

Alopecia areata, hair loss disorder, is an autoimmune disease which results from certain abnormalities in the immune system. In this condition, the immune system that works in defense of the body against foreign invasions, misinterpret hair follicles as harmful foreign agents and hence launch an attack against them. This caused severe hair fall resulting in bald patches on scalp.

It is shocking to see symptoms of this condition among kids. Unfortunately, the disorder is observed among adolescent and younger kids owing to underdeveloped immune system. It is observed that this meek system is extremely sensitive to factors like stress, wrong eating habits and more. Therefore, the children become predisposed to this hair loss condition and experience its bouts as a response to stress.

Moreover, the condition seems to run in families as it may get passed on from one generation to another through hereditary factors. Therefore, children with either of members, falling in blood relation, suffering from this condition are exposed to facing hair loss due to Alopecia. The symptoms of the same are observed in the form of round hairless patches on the scalp. The patches may intensify after the occurrence of episodes of emotional turbulence and stress.

The condition is the result of body’s immune system launching an attack on the hair follicles. More than 5 percent of kids suffering from this hair loss condition often go on to develop alopecia totalis which is characterized by the total loss of hair on the scalp. Therefore, in order to prevent the further worsening of the disorder, it is better to conduct a timely diagnosis so as to initiate the right treatment. In case, the bald patch fails to eliminate with the natural re-growth of the hair, it is advisable to use topical medicines on the affected regions. Some of the strong topical creams popularly recommended for the treatment of the condition are Temovate and Diprolene. Sometimes, a potent steroid, Celestone is also injected at the affected side to trigger immediate hair re-growth. The growth of initial few strands is observed right after 4-6 weeks following the treatment. The dosage of medicines however needs to be given after every 4-6 weeks until a normal growth cycle is resumed.

Adult ADHD Signs & Struggles

Adult ADHD symptoms come under the groups of inattentiveness, restless & impulsive behaviour. The range & acuteness of symptoms differ across individuals – though they should be recent & incessant, continual since infancy & the reason for grave problems in various life spheres for an identification to be done.

One important common point which psychologists note about ADHD is that adults with this disorder have a tendency of seeking therapy when they are facing considerable work, relationship issues or duo. These people mostly visit their psychologists when disheartened, having faced repetitive failures in life, incapable of achieving their objectives & having failed to live up to the expectations of people around.

Job & schooling are duo areas wherein the disorder tends to exert a major toll. Time management & priority-setting are regular challenges & relationship with authority-figure buddies or kin tends to be bumpy. Individuals with this disorder are at a greater risk of being depressed, anxious & abusing alcohol, & could be temperamental or susceptible to fury fits. Topping it all, they have a tendency of accumulating traffic breaches & accident cases, & it could be tricky for them in keeping their occupations.

How Adult ADHD is diagnosed?

In case one thinks that one has ADHD & wishes to follow therapy then select a physician or some qualified mental health expert with training in identifying & diagnosing ADHD.

The expert would most probably be requesting physical, lab, mental & psychological testing for corroborating symptoms aren’t the outcomes of any other condition with signs mimicking ADHD. Several of these entail brain injuries, psychologically related issues, learning problems, addicted to alcohols or drugs, being anemic, being exposed to lead & side-effects of prescription-only & OTC medications or herbal cures.

Surveys like the Wender Utah Rating Scale are deployed for assessing if ADHD signs were existent during infancy.

The medical panel might even be interviewing individuals near & dear to the person, inclusive of parents, partner, brother/ sister or long-time buddy. Grades in school & vocation assessments could even aid in shedding light on the signs of ADHD & their acuteness.

The present ADHD conditions were devised for using with kids, & makes them lesser than perfect for assessment in adults. Regrettably, they are yet the sole analytical tools presently obtainable.

Presence of 6 or more of the below mentioned signs of inattentiveness indicate principally inattentive type ADHD, as per the APA’s analytical criteria.

  • Mostly failing to be heedful about finer details or making sloppy errors in assignment at school or vocation.
  • Often faces issues staying on chore.
  • Oftentimes doesn’t appear to be listening when he/ she is spoken to in a direct manner.
  • Faced problems trying to organize activity & task.
  • Mostly skips task which needs continued mental efforts.
  • Often tends to lose some equipments, tool or book linked to some assignment or activity.
  • Sidetracked easily.
  • Frequent forgetfulness.

Presence of 6 or more of the below mentioned hyperactivity signs indicate mostly hyperactive impulsive type ADHD. Such signs & symptoms entail though are not restrained to:

  • Mostly fidgety & squirmy behaviour when seated.
  • Often leaving seat in scenarios necessitating one to remain seated.
  • Mostly experiencing restless feelings.
  • Often faces difficulty engaging in leisurely activities silently.
  • Appears to be motor-impelled & persistently on-the-go.
  • Excessive speaker.
  • Blurting out answer prior to queries being completed.
  • Experiences difficulty waiting for his/ her turn.
  • Oftentimes interrupting others.

When there are 6 or more signs from every area present then it is indicative of combined-type ADHD.

The downbeat effects of ADHD can really impair & damage the person concerned. Opting for therapy is mostly a quality of life problem. Envisage having blurry eyesight for three decades & you learnt a way of compensating, but that doesn’t essentially mean that the ophthalmologist should not offer you eye glasses.

Alexander Technique and Feldenkrais

Increasing numbers of patients are enthusiastically endorsing duo treatments Alexander technique and Feldenkrais for lessening pains & disablements arising from several musculoskeletal problems. Here’s how these treatments differ in their approach at providing respite.

Alexander technique is a means of feeling betterment, & moving in a more relaxed & comfy manner – what’s intended innately. This technique is ideal for those:

  • Ailing from repeated strain injuries or carpel tunnel syndrome, osteoarthritis among several others.
  • Suffering from backaches or stiffness in shoulder & neck areas.
  • Experiencing discomfort while seated at the laptop for protracted spans of time.
  • From professions like singing, music, acting, dancing or sports & feeling that they aren’t performing at their top potential.
What One Mustn’t Expect

For starters, there’s no peeling off clothing needed or any type of special garb needed – although since table work mostly is forming part of the lessons, female participants generally are more comfy donning jeans, leggings, trousers instead of skirts.

Alexander technique sessions aren’t agonising and there’s no physical aggressiveness about the work. Conversely, it is a practice of permitting participants in releasing their tensions & detrimental habits which are accountable for their bodily complaints – at a pace best-suiting the person.

What are Alexander Technique Practitioners doing during lessons?

During lessons, teachers would observe the participant’s postural & motion patterns while additionally
supplementing the visual info in a rather vital manner by deploying hands & in a gentle manner placing them on areas of the body like back, shoulder, neck. Hands are used for getting more detailed info regarding one’s patterns of respiration & movement.

Teachers would perhaps request the participants on performing some basic motions – possibly walk, stand up or be seated on a chair – whilst the teacher’s hands are placed on the entrant’s body for to-&-fro sending & receiving of info as the teacher lightly guides the entrant’s body for encouraging restricted muscle tensions to be released.

Innately, every instructor differs from the next one in his/ her approach to teaching the Alexander technique. Several might be talking & explaining more initially while some preferring to spend greater amount of time in the initial lessons to just help the entrant in getting a novel experience of ease & suppleness. Analogously, several tutors would highlight some comparatively basic motions, permitting the effect to be carried over into every activity of the person while some teachers opt to work with patients in a broad assortment of applications.

What is the duration of the lessons & how many would be needed?

An Alexander technique lesson generally would be lasting amid 30-45 minutes long and perhaps following some lessons teachers would be getting an idea of how soon the participant is progressing. At the onset, students are generally requested to attend the sessions often, possibly 2-3 times/ week in case doable though later on once the pupil starts showing improvement then lessons would be seven days or more apart.

What is group work done by Alexander teachers?

Several teachers feel that when they work with people in group settings they could assist more numbers of individuals than would even have been doable in one-on-one sessions. Group work under the apt circumstances could be quite an effectual means of teaching.

Feldenkrais Method

It is a movement practice that helps by harnessing one’s natural capability of sensing, exploring, learning & growing – being more heedful to one’s body as one moves, scrutinizing oneself for seeing oneself as one really is. In this process one uncovers tension-eliciting practices which show the fundamental reason for a person’s stresses or limitations. With the Feldenkrais lessons unfolding, one discovers ease of motion & the pathway of smallest amount of resistance.

Duo key modes constitute this method namely:

Awareness-through-movement – It is basically verbal-directed motion exploration generally a group work.

Functional Integration – It is a mode to work with people wherein practitioners mainly use their hands to guide them via a series of motions which are all linked to a particular functional idea. The function opted is mostly one which would be highlighting the manner in which a habit of motion might be contributory to a some concerns one might be having, whether it is pains or a skills one is keen on improving.

The spotlight is on least effort, effortlessness of motion & learning. One isn’t stretching or straining in such Feldenkrais sessions. One is seeking more freedom & easiness via consciousness & comprehension. In this manner, the advantages realized during sessions could be repeated & instantly be applied to other life scenarios.

All Feldenkrais practitioners have been through a 4-yr training phase prior to conducting private & group sessions.

Strangest Medical Problems In People

Our human body is an intricate machine wherein some component could malfunction and lead to strange sicknesses & behaviours – a number of them yet baffling sufferers as well the doctors.

Here’s a listing of mystifying, jaw-dropping sicknesses.

Aquagenic Urticaria

Teen Australian girl Ashleigh Morris cannot enjoy a swim, soak in heated water baths or unwind in showers following a stress-ridden day as she has an allergy to water irrespective of the temperature. Merely perspiration could trigger agonizing rashes on her body. The girl has been suffering from this rather atypical skin condition termed Aquagenic Urticaria since fourteen years of age which is known to afflict merely some people across the globe.

 

A Dieter Dream Come True

Fifty-nine-year old Perry can binge on whatever foods he wants & never pack the pounds due to a condition he suffers known as lipodystrophy which makes his body into a swift fat-burning machine.

Although been a plump boy till twelve, his flabbiness nearly shed overnight. The Essex-resident consciously consumed more for gaining weight though it failed to show any effect. After enduring almost ten years of testing he was eventually identified with a condition wherein his body tends to produce 6 folds the regular amount of insulin.

 

Allergic to Smog

For majority of the individuals chatting on their cell phones, preparing their meals in the microwave oven or taking their car out are indispensable and part of everyday modern-day existence. However, being able to complete these tasks is not possible for the thirty-nine-year-old Debbie Bird who ails from allergy to mobiles & microwaves. Due to her sensitivity to electro-magnetic field-emitting devices like mobiles, microwave oven, laptops & also some models of vehicles she gets excruciating skin rashes & her eyelid areas would be swelling up to nearly thrice their normal size whenever she’s in close proximity to them. For counteracting this weird condition, the woman has changed her abode to make it totally free from any sort of smog in an endeavour at trying & staying healthy. She states that she couldn’t any longer be doing things which she earlier never gave a second thought about and confesses to her everyday existence being gravely impacted as a result of her medical condition.

 

Ice-Proofed Man

Wim Hof is the guy who has swum underneath ice, stood in ice-filled containers, successfully scaled Mount Blanc in just a pair of short pants, world-records holder & forever game to any new challenge. Researchers don’t have any explanation for why Hof is capable of withstanding & also thriving in a temperature range which can be deadly for regular individuals.

 

Chiari Malformation

Tot Rhett Lamb exhibits crankiness alike other kids his age though what makes him totally different is his atypical medical illness due to which he is not able to have any shut eye at all. Lamb’s wide-awake almost twenty-four hours of the day & his medical problem has perplexed his physicians & parents for several years. In a bid to establish what precisely troubled the little lad clockwise shifts were taken by his parents & physicians for observing his snooze-deprived moods.

Subsequent to several contradictory opinions, his parents eventually came to know what has been the root cause of this problem. The boy was identified with a rarely occurring medical condition known as chiari malformation wherein literal squeezing of the brain into the spinal column occurs leading to strangulation of the brain stem (an organ responsible for all the essential functions controlling verbal communication, slumber, respiratory & also cardiovascular system).

 

Collapsing on Laughing

U.K. based Kay Underwood suffers from cataplexy wherein nearly any kind of strong sentiment drastically weakens her muscles – be it – being exhilarated, angry, fearful, surprised, awe-struck & also embarrassed could be causing the sufferer to experience sudden collapsing.

Underwood was identified with cataplexy over 5 years back, at one time has been reported to collapse over forty times in just one day. She speaks about how onlookers find it rather strange when it occurs & it can be tough coping with reactions of unfamiliar persons.

Alike majority of the cataplexy patients, Kay is even narcoleptic (a disorder wherein the individual would suddenly dose off to sleep sans any caveat). Narcolepsy afflicts close to thirty thousand individuals in the United Kingdom & around seventy percent of these individuals even ail from cataplexy.

 

Orgasmic 200 Times Daily

Twenty-four years old Sarah Carmen of United Kingdom is one super-sensitive woman who seems to catch fine vibrations from virtually anything. The woman is suffering from PSAS (permanent sexual arousal syndrome) that heightens blood supply to her sexual organs. She confesses to her men not having to take that many efforts as she climaxes a lot & without much arousal needed. She holds the pills responsible for her strange condition wherein she cites arousal & endless climaxes lasting several hours & her guy being astonished at the number of times she would get orgasmic. She even reports experiencing the Big O post-sex. Within 6 months, she cited having 150 & have experienced nearly two hundred orgasms. Sarah’s come clean about wanting to wear herself out by experiencing as many climaxes as she could so that they would stop & she could finally be getting some peace.

 

Memory like an Elephant

This is an account of an amazing woman in her forties, Jill Price who simply doesn’t forget anything.

Scientists from University of California, Urvine have been researching this enthralling case of an individual who’s got ceaseless, uncontainable & instinctive memory of her past & myriad public incidents. You could just arbitrarily select some date from over two decades back & query her on it and she will offer detailed, provable details regarding what transpired to her during that particular day & whether there were any important news happenings on matters which interest her. Price can even recollect which day-of-the-week it was & the climatic conditions during that time. Her rather remarkable condition lately got christened as ‘hyperthymestic syndrome’ in the ‘Neurocase’ medical journal.

 

Non-stop Hiccups

Lincoln-based songster Chris Sands would hiccup as frequently as 2-sec intervals – and at times also when sleeping. Trying an array of remedies inclusive of practising yoga to hypnotizing himself Sands hasn’t yet found a solution to his incessant hiccupping. He deems that his issue is stemming from an acid reflex problem arising from a damage-ridden value in his abdomen. Chris states that in case levels of stomach acids are acute then the doctors would perform keyhole surgical procedure wherein a section of his abdomen would be wrapped around the valve for tightening it.

As a result, Chris’s singing career has faced a major setback and physicians of QMC, Nottingham would be placing a tubular structure inside his abdomen for monitoring his stomach acid levels & deciding on whether surgical intervention is doable.

 

Allergic to Semen

Approximately a hundred females in the United Kingdom have allergy to their mate’s seminal fluid (one carrying sperms) – medically termed as human seminal plasma hypersensitivity. The reason for this is since semen is a carrier of several proteins; it could activate allergic responses in vulnerable females.

Indications of semen allergy generally entails reddishness, stinging sensation & swellings shortly following sexual contact, whenever seminal fluids would be coming in contact with the skin. It could be averted by the guy using condoms. But, in case such couples are keen on bearing children then assisted reproduction techniques could be deployed.

 

Tic-Tac Only Diet

Teen Natalie Cooper ails from a baffling condition making her fall sick on each instant she consumes any or nearly any food, though the sole item that could be stomached by the girl is Tic-Tac mints. For inexplicable reasons, physicians are clueless about this state which means that Cooper would be getting the remaining part of her nourishment from a specifically devised formulation which would be fed via a tubular structure.

Strangest Medical Problems In People

Our human body is an intricate machine wherein some component could malfunction and lead to strange sicknesses & behaviours – a number of them yet baffling sufferers as well the doctors.

Here’s a listing of mystifying, jaw-dropping sicknesses.

Aquagenic Urticaria

Teen Australian girl Ashleigh Morris cannot enjoy a swim, soak in heated water baths or unwind in showers following a stress-ridden day as she has an allergy to water irrespective of the temperature. Merely perspiration could trigger agonizing rashes on her body. The girl has been suffering from this rather atypical skin condition termed Aquagenic Urticaria since fourteen years of age which is known to afflict merely some people across the globe.

 

A Dieter Dream Come True

Fifty-nine-year old Perry can binge on whatever foods he wants & never pack the pounds due to a condition he suffers known as lipodystrophy which makes his body into a swift fat-burning machine.

Although been a plump boy till twelve, his flabbiness nearly shed overnight. The Essex-resident consciously consumed more for gaining weight though it failed to show any effect. After enduring almost ten years of testing he was eventually identified with a condition wherein his body tends to produce 6 folds the regular amount of insulin.

 

Allergic to Smog

For majority of the individuals chatting on their cell phones, preparing their meals in the microwave oven or taking their car out are indispensable and part of everyday modern-day existence. However, being able to complete these tasks is not possible for the thirty-nine-year-old Debbie Bird who ails from allergy to mobiles & microwaves. Due to her sensitivity to electro-magnetic field-emitting devices like mobiles, microwave oven, laptops & also some models of vehicles she gets excruciating skin rashes & her eyelid areas would be swelling up to nearly thrice their normal size whenever she’s in close proximity to them. For counteracting this weird condition, the woman has changed her abode to make it totally free from any sort of smog in an endeavour at trying & staying healthy. She states that she couldn’t any longer be doing things which she earlier never gave a second thought about and confesses to her everyday existence being gravely impacted as a result of her medical condition.

 

Ice-Proofed Man

Wim Hof is the guy who has swum underneath ice, stood in ice-filled containers, successfully scaled Mount Blanc in just a pair of short pants, world-records holder & forever game to any new challenge. Researchers don’t have any explanation for why Hof is capable of withstanding & also thriving in a temperature range which can be deadly for regular individuals.

 

Chiari Malformation

Tot Rhett Lamb exhibits crankiness alike other kids his age though what makes him totally different is his atypical medical illness due to which he is not able to have any shut eye at all. Lamb’s wide-awake almost twenty-four hours of the day & his medical problem has perplexed his physicians & parents for several years. In a bid to establish what precisely troubled the little lad clockwise shifts were taken by his parents & physicians for observing his snooze-deprived moods.

Subsequent to several contradictory opinions, his parents eventually came to know what has been the root cause of this problem. The boy was identified with a rarely occurring medical condition known as chiari malformation wherein literal squeezing of the brain into the spinal column occurs leading to strangulation of the brain stem (an organ responsible for all the essential functions controlling verbal communication, slumber, respiratory & also cardiovascular system).

 

Collapsing on Laughing

U.K. based Kay Underwood suffers from cataplexy wherein nearly any kind of strong sentiment drastically weakens her muscles – be it – being exhilarated, angry, fearful, surprised, awe-struck & also embarrassed could be causing the sufferer to experience sudden collapsing.

Underwood was identified with cataplexy over 5 years back, at one time has been reported to collapse over forty times in just one day. She speaks about how onlookers find it rather strange when it occurs & it can be tough coping with reactions of unfamiliar persons.

Alike majority of the cataplexy patients, Kay is even narcoleptic (a disorder wherein the individual would suddenly dose off to sleep sans any caveat). Narcolepsy afflicts close to thirty thousand individuals in the United Kingdom & around seventy percent of these individuals even ail from cataplexy.

 

Orgasmic 200 Times Daily

Twenty-four years old Sarah Carmen of United Kingdom is one super-sensitive woman who seems to catch fine vibrations from virtually anything. The woman is suffering from PSAS (permanent sexual arousal syndrome) that heightens blood supply to her sexual organs. She confesses to her men not having to take that many efforts as she climaxes a lot & without much arousal needed. She holds the pills responsible for her strange condition wherein she cites arousal & endless climaxes lasting several hours & her guy being astonished at the number of times she would get orgasmic. She even reports experiencing the Big O post-sex. Within 6 months, she cited having 150 & have experienced nearly two hundred orgasms. Sarah’s come clean about wanting to wear herself out by experiencing as many climaxes as she could so that they would stop & she could finally be getting some peace.

 

Memory like an Elephant

This is an account of an amazing woman in her forties, Jill Price who simply doesn’t forget anything.

Scientists from University of California, Urvine have been researching this enthralling case of an individual who’s got ceaseless, uncontainable & instinctive memory of her past & myriad public incidents. You could just arbitrarily select some date from over two decades back & query her on it and she will offer detailed, provable details regarding what transpired to her during that particular day & whether there were any important news happenings on matters which interest her. Price can even recollect which day-of-the-week it was & the climatic conditions during that time. Her rather remarkable condition lately got christened as ‘hyperthymestic syndrome’ in the ‘Neurocase’ medical journal.

 

Non-stop Hiccups

Lincoln-based songster Chris Sands would hiccup as frequently as 2-sec intervals – and at times also when sleeping. Trying an array of remedies inclusive of practising yoga to hypnotizing himself Sands hasn’t yet found a solution to his incessant hiccupping. He deems that his issue is stemming from an acid reflex problem arising from a damage-ridden value in his abdomen. Chris states that in case levels of stomach acids are acute then the doctors would perform keyhole surgical procedure wherein a section of his abdomen would be wrapped around the valve for tightening it.

As a result, Chris’s singing career has faced a major setback and physicians of QMC, Nottingham would be placing a tubular structure inside his abdomen for monitoring his stomach acid levels & deciding on whether surgical intervention is doable.

 

Allergic to Semen

Approximately a hundred females in the United Kingdom have allergy to their mate’s seminal fluid (one carrying sperms) – medically termed as human seminal plasma hypersensitivity. The reason for this is since semen is a carrier of several proteins; it could activate allergic responses in vulnerable females.

Indications of semen allergy generally entails reddishness, stinging sensation & swellings shortly following sexual contact, whenever seminal fluids would be coming in contact with the skin. It could be averted by the guy using condoms. But, in case such couples are keen on bearing children then assisted reproduction techniques could be deployed.

 

Tic-Tac Only Diet

Teen Natalie Cooper ails from a baffling condition making her fall sick on each instant she consumes any or nearly any food, though the sole item that could be stomached by the girl is Tic-Tac mints. For inexplicable reasons, physicians are clueless about this state which means that Cooper would be getting the remaining part of her nourishment from a specifically devised formulation which would be fed via a tubular structure.

Alzheimer’s disease Grey’s Memory Test

What did you do last Christmas? Which location did you decide upon for honeymooning? Start counting backwards from one hundred by 7. Bear in mind the following trio-word series: bus, castle, fork.

These are some of the battery of queries put forth by the lead stars of ‘Grey’s Anatomy’ to Alzheimer’s disease sufferers for ascertaining if they qualify for admission into a scientific study for the current season’s show.

However, in case one is seated on a divan 5 minutes after racking one’s brains trying to recollect the word ‘castle’ must one be worried regarding one’s own brain health & how precise is this test to gauge Alzheimer’s disease risk?

Alzheimer’s disease Grey’s Memory Tests

Though the test on the television show isn’t recognized by name, several of the queries such as 3-word memory sequences & count-back directives are part of the thirty-point series of questions in MMSE initiated in the mid-seventies. It is widely deployed in evaluating cognitively for any failure in memory. It is basically a test to screen people hence it isn’t delving deep into their cognitive performance across diverse regions of cerebral performances. Other forms of queries that are part of the MMSE entail:

  • To draw particular images.
  • Perform a 3-step order like ‘hold a paper, now folding it in the middle & placing it on the ground’.

People need to understand that the queries deployed by the actors in their story bound adaptation of the testing are merely a sample of the sum number of queries which would be part of the actual testing or else the restricted numbers of replies aren’t that noteworthy for the avg. individual. Also the query of whether patients could recollect the location where he/ she honeymooned is not expected to be part of the actual testing – this is more of a distant memory that is generally kept aside till advanced staging of the condition.

Aged Moments versus Caveat Signs

So, what’s the reason for not remembering the just mentioned word sequencing or the location of your vehicle parking at the super-mart? You possibly were inattentive or were doing multiple tasks at that time or merely sidetracked. These daily aged moments don’t essentially mean red-alert presence of dementia.

All of us tend to forget matters now-&-then. Not recalling is also important else imagine how jam-packed our brains would otherwise be and one would not be able to get sound slumber at nights.

Though what is a matter of concern is when memory alterations last for 4-6 months, impeding one’s capability of functioning in an independent manner at job or at your abode, & when buddies & kin spot an alteration in one’s capabilities or behaviourisms. In case, yourself or a near & dear one experiences any of such signs & symptoms of likely dementia then one must discuss with a physician & get examined.

Even in this situation, one needs to understand that loss of memory does not involuntarily translate to one having AD that would entail language issues, feeling disoriented & facial-identification problems amongst its other signs & symptoms. Loss of memory could be an indication of a minimum of seventy-five diverse medical problems – inclusive of deficit of vitamin B12, depression, being distressed emotionally, thyroid conditions & drug side-effects.

Alzheimer’s disease is a highly pervasive dementia form that accounts for around seventy per cent of cases among individuals in the age seventy-one years onwards. However, it is observed to strike merely 5% of individuals in the age of sixty-five & seventy-four years old. Younger one is, greater the likelihood that a memory-linked problem isn’t Alzheimer’s disease.

There is a common tendency in people to excessively fret regarding memory failure since it is a thing that many are fearful about. However, as there are several diverse reasons for causing it & several of such conditions could be reversed hence it is crucial that one seeks medical examination at the earliest.

Memory Tests & their part in actual Alzheimer’s trials

It is always a challenge to diagnose Alzheimer’s disease, as the sole means of definitely determining the existence of a condition is by examining brain cells once some person has expired. Rather, physicians are evaluating the possibility of Alzheimer’s disease with a host of testing which even seek for excluding other likely reasons for dementia.

They could comprise of a comprehensive exam of medical past, physical exam, laboratory testing of blood, urine & at times spinal fluids & brain scanning alongside cognitive tests. Physicians with expertise in treating Alzheimer’s could spot the condition with a ninety per cent precision.

At the time of cognitive testing, doctors are checking wide-ranging brain tasks  – assessment not merely limited to memory – however a person’s capability to calculate, attentiveness, insight, judgemental capability & the manner in which they are prioritizing things. Specialists are basically examining an array of aspects since individuals are thinking in so many diverse ways.

Alzheimer’s disease Scientific Studies

The story-bound ‘Grey’s Anatomy’ scientific study stresses upon the significance of actual-life study. The Alzheimer’s Association points out that presently there are over a hundred scientific studies which require fifty thousand participants – having or not having Alzheimer’s. These studies are probing novel means of detecting, treating & preventing Alzheimer’s & associated forms of dementia.

Though scientists could not proffer regular cognitive state examinations by Doctor McDreamy hence in case yourself or a close one is tackling with this disease diagnoses then seek out a trial which might be suitable for you via checking out the website ‘ClinicalTrials.gov’ or Alzheimer’s Assn. Trial Match Program. Studies have shown that individuals partaking in trials have a tendency of doing slightly better as compared to individuals at an analogous staging of Alzheimer’s that aren’t part of studies, the assn. states.

Top Ten Ghastly Medical Abnormalities

Side-show days showcasing the so-dubbed ‘freaks-of-nature’ are bygones now, though the conditions causing such so-dubbed ‘weirdoes’ are yet among us. Here is a listing that highlights the most wacky (& at times shocking) abnormalities of medical science.

1.Lutz-Lewandowsky epidermodysplasia verruciformis

Additionally known as Epidermodysplasia verruciformis, is a exceptionally rare heritable condition wherein wart formations surface over the skin.Usually the foot & hand areas are affected & even though it could commence anywhere between forty-five & sixty-five years of age, it usually arises in those amid the age group of 1-20 years old. There isn’t any identified effectual therapy for the condition although surgical intervention could be deployed for wart removal. Regrettably, post-surgery these horrendous wart formations would re-surface. It is approximated that those ailing from this disorder would require a minimum of duo surgical interventions annually for removing them on every instant they recurred. During 2007, a person ailing from this condition underwent surgical procedure for the same & an eye-popping removal of 13 lbs of warts recorded – excision of ninety-five percent of warts was accomplished during the surgical procedure.

2. Myositis Ossificans Progressiva

Also termed as FOP (Fibrodysplasia Ossificans Progressiva) is a rather atypical condition causing portions of the body (like tendon, muscle, ligament) to transform into bones on facing damage. It could mostly be causal to fusing together of damage-ridden joint areas which hinder movements. Regrettably, operative excision of the bony growths is ineffectual as the body’s self-healing mechanism re-forms the excised bone. Making the issue even direr is the rarity of this condition hence often erroneously diagnosed as being cancer which leads to physicians biopsying these growth that triggers shoddier development of such bony lump formations. Harry Eastlack’s case is the much-remembered one wherein the extent of ossification that his body underwent by his death left him with solely his lip areas capable of movement. The man’s skeletal remains are displayed in the Mutter Museum and continue to grab much attention due to the uniqueness of his condition. This disorder is incurable.

3. Elephantiasis

It is a disorder wherein skin thickens. Regrettably, it is a condition which could develop in any person since it is due to parasitic worm forms being transmitted on being bitten by mosquitoes. As a result, it is rather common in the tropics & African area. A somewhat diverse type of the disorder arises via skin contact with particular forms of soils. In several Ethiopian areas, nearly six percent of the populace ails from such condition and is the commonest of disablements worldwide. Widespread endeavours are on-going & it is anticipated that it would be ably annihilated from earth by the end of the next decade.

4. Cutaneous Porphyria

It is a condition which is causal to blistering, excessive hair, swellings & necrosis in skin. Reddish-coloured tooth & finger nail areas are other signs of this disorder & on being exposed to the sun’s rays, the person could have purplish, pinkish, brownish or blackish urination. The condition is believed to be linked to several ware-wolfs & blood-sucking vampires tales in history, wherein a person ailing from this condition (who would be living a solitary existence) may have been wrongly believed to be monstrous. The condition is component of the generalized grouping of conditions known as porphyries that envelop an array of conditions (mentally & physically) because of particular enzymatic excess manufacture in the body. The condition got christened from a word ‘porphura’ – meaning purplish pigment.

5. Progeria

Also known as Hutchison-Gilford Progeria syndrome, it is causal to untimely aging – with such swiftness that a young kid could appear similar to a rather elderly person or an alien-like appearance. The condition is particularly attention-grabbing for researchers as it might offer hints into the innate process of growing old in males. Genetic mutation is the reason for this condition & isn’t passed down generations. It is incurable & majority of the kids having this condition would manage to survive past 13 years of age- generally deaths from strokes or heart attacks (conditions generally linked to older age) are their sealed fate.

6. Möbius Syndrome

It is a rarely occurring condition wherein the muscles of the face develop paralysis. In majority of the situations, the eyeballs are incapable of moving sideways.The condition tends to make sufferers seem ‘expressionless’ or dullish or non-interested as he/ she doesn’t exhibit any face expressions – at times making individuals in believing that they are discourteous. People suffering from such condition would exhibit regular mental growth. The reasons for this condition arising isn’t totally comprehended & there’s no therapy apart from having to address the signs (like feeding incapability as an infant).

7. Proteus Syndrome

The condition leads to excess bone & skin developments & often coming with tumor formations. Merely two hundred cases have been substantiated globally following its official discovery during the later part of the seventies. It could be likely for an individual to be having a minor version of such disorder that could be going unidentified. Joseph Merrick – the Elephant Man is perhaps the largely well-known case of this disorder and the reason for it becoming so extensively identified. People suffering from this condition would have normal I.Q. & brain functioning.

8. Fetu In Fetu

Thirty-six-year old Indian Sanju Bhagat had a full-term pregnancy with his own twin. As placental tissue was lacking, there was direct attachment of twin within him to his body’s blood circulation.Delivery of the twin was done by physicians who has severe malformation & failed in surviving.

Fetus in fetu is an exceptionally atypical condition wherein a twin in some manner develops connection (internal or partially external) to its twin whilst yet inside the uterus. There have been people in whom the fetus in fetu stayed within the host twin unidentified till it started becoming problematic. In rather prevalent situations, the indications are apparent from the inception & are oftentimes wrongly believed to be cancer or cyst. There was also a case of a seven-year-old boy identified with being a carrier of his own twin when the parents observed some movement in his tummy.

9. Diphallic Terata

Also known as PD (penile duplication) is a disorder wherein a baby boy innately has duo penis organs. With solely one thousand cases cited, it is an atypical condition and those ailing from it are even at a greater risk of suffering from spina bifida as compared to males having a single penile organ.An individual with PD could be urinating from duo penises and in majority of these men, the two penile organs are situated sideways to one another & analogously sized, though sporadically a bigger-sized one would be sitting underneath the smaller-sized penis. According to available stats, 1 from five and a half million males in the U.S. has duo penis organs.

10. Diprosopus

Diprosopus is a rarely occurring condition wherein facial duplication on the head occurs. It mustn’t be mixed with the disorder fetus in fetu wherein duo diverse fetuses are joined.Sonic hedgehog homolog protein is believed to be the offender. It is the one responsible for facial constitution & excess of it could be giving the person another face as a replica image. Deficits of this protein could lead to underdevelopment of face features. Babies having such anomaly are usually stillborns though there has been a case of an Indian baby born with this anomaly but managing to live duo months prior to suffering from a heart attack.

Salon Stroke Syndrome

There is a spine-tingling association in-between going in for a hair wash at a salon and stroke risk. Salon-stroke syndrome is a condition that develops as a consequence of the arteries in the neck that travel to the brain developing strain. The pinching, kinking of such arteries (vertebral/carotid) could lead to the development of clots.

It is a startling scenario as several individuals are oblivious that getting their hair done is placing them at a risk of suffering from stroke. Typically in salons the neck is bent back on a sink for lengthy periods of time particularly during hair washing & conditioning. This posture could be contributory to diminished blood flow to the brain leading to tear in the neck arteries that can elicit a stroke. The neck arteries convey blood to the section of the brain which is in charge of thought process, speech and behaviour. In case the brain is denied its regular blood supply for extended time then lasting harm could occur. The blood vessels going up the backside of the neck pass via a fairly constricted bony canal and with aging it narrows even further. Among aged people and those with neck arthritis there could also be presence of jagged edges to it that increases their vulnerability.

Varied stroke symptoms arising as a result that include slurry speech, vertigo, feeling nauseous, puking, one-sided weakness felt in the facial region during or post-shampooing.

Individuals at elevated risk of suffering stroke or having CAD (carotid artery disease – plaque accruement within the arteries which can slacken or obstruct blood flow to the brain) must steer clear from tipping their necks in the backward direction in beauty salons or otherwise. Generally Salon-stroke syndrome generally develops in elderly females, particularly cervical arthritis patients. For reducing the risk or preventing the condition all particularly elderly individuals having neck arthritis to not get their hair washing done at an inclination not crossing fifteen to twenty degrees. Rather to be on the safer side, leaning forwards over the washing bowls or the use of padding or cushioning for the neck are advisable.

Strokes are deemed to be linked to the time and force of neck motion alongside factors prevalent with going old like atherosclerosis.

Salon-stroke syndrome could additionally develop among individuals who arch their neck backwards for lengthy spans of time for reasons like during dentist’s appointments or when they receive anesthesia. Other triggers that generally need 10 minutes of neck over-extension are fair ground rides, yoga, sit up exercise moves or ‘Golden Gate Bridge Syndrome’ provoked by excessively straining to look up.

Salon-stroke syndrome atypically occurs and physicians maintain that getting one’s hair done traditionally is yet safe. Physicians recommend that placement of cushions must be done in salons during hair washing rituals so that the neck does not get overextended. Perhaps high-tech, bio-engineered shampooing bowls and seating arrangements are the key to a risk-free hair-rinsing experience. However, it would translate to a costlier hair wash. How many of us are willing to shell that extra buck on health grounds even though the likelihood of suffering a stroke due to hair washing in salons is pretty slim.

Related Posts with Thumbnails