Caroli disease can be defined as a rare genetic disorder marked by dilation of intrahepatic bile duct. Caroli disease can be of two types. The first and the most frequently occurring type is simple or the isolated cases, in which the bile duct get widened due to ectasia. The other type is the more complex version of the condition and is mostly caused by Calorie Syndrome; however, some cases of complex Caroli disease are also linked with congenital hepatic fibrosis and hypertension. Till date, no medical study has found out the difference between caused of simple and complex Caroli disease. Certain cases of Caroli disease have also been linked with polycystic kidney diseases and liver failure. As mentioned earlier, Caroli disease is a rare condition and affects around 1 in every 1,000,000 people.  [...]

Our human body is an intricate machine wherein some component could malfunction and lead to strange sicknesses & behaviours – a number of them yet baffling sufferers as well the doctors. Here’s a listing of mystifying, jaw-dropping sicknesses.Aquagenic UrticariaTeen Australian girl Ashleigh Morris cannot enjoy a swim, soak in heated water baths or unwind in showers following a stress-ridden day as she has an allergy to water irrespective of the temperature. Merely perspiration could trigger agonizing rashes on her body. The girl has been suffering from this rather atypical skin condition termed Aquagenic Urticaria since fourteen years of age which is known to afflict merely some people across the globe.A Dieter Dream Come TrueFifty-nine-year old Perry can binge on whatever foods he  [...]

From astonishing survivals to wacky medical conditions, the medical world is brimming full with jaw-dropping accounts. Here is simply a sample of the myriad accounts that the medical fraternity has to present. Trimethylaminuria Actually, the foremost cited case of this condition in medical records occurred in the seventies. It is an atypical metabolic condition causal to a flaw in a particular enzyme which leads to breakdown of compound trimethylamine (set free by protein-assimilating bacterial form that live in our abdomen). As a result, the sufferer would start emitting the compound while perspiring, urinating & via other body fluids. Hence, what one essentially gets is a persistent body smell evocative of rancid fishes - the reason for it having infamously earned the pet name ‘fish  [...]

Side-show days showcasing the so-dubbed ‘freaks-of-nature’ are bygones now, though the conditions causing such so-dubbed ‘weirdoes’ are yet among us. Here is a listing that highlights the most wacky (& at times shocking) abnormalities of medical science. 1.Lutz-Lewandowsky epidermodysplasia verruciformis Additionally known as Epidermodysplasia verruciformis, is a exceptionally rare heritable condition wherein wart formations surface over the skin.Usually the foot & hand areas are affected & even though it could commence anywhere between forty-five & sixty-five years of age, it usually arises in those amid the age group of 1-20 years old. There isn’t any identified effectual therapy for the condition although surgical intervention could be deployed for wart removal.  [...]

Lou Gehrig Disease is a condition marked by slow death of particular nerve cells or motor neurons of the spinal cord & brain which are responsible for controlling muscles which facilitate a person in moving varied regions of the body. It is also known as Amyotrophic lateral sclerosis (ALS). Individuals with Lou Gehrig Disease experience gradual but certain disablement. The rate at which the condition deteriorates differs from person to person. A number of individuals live with Lou Gehrig Disease though with passage of time it makes it trickier in walking, eating, speaking, breathing and swallowing. Such issues could be causal to injuries, illnesses & finally fatality. It could be quite intimidating to discover that one has Lou Gehrig’s disease. Discussing with an expert, going in  [...]

There is a spine-tingling association in-between going in for a hair wash at a salon and stroke risk. Salon-stroke syndrome is a condition that develops as a consequence of the arteries in the neck that travel to the brain developing strain. The pinching, kinking of such arteries (vertebral/carotid) could lead to the development of clots. It is a startling scenario as several individuals are oblivious that getting their hair done is placing them at a risk of suffering from stroke. Typically in salons the neck is bent back on a sink for lengthy periods of time particularly during hair washing & conditioning. This posture could be contributory to diminished blood flow to the brain leading to tear in the neck arteries that can elicit a stroke. The neck arteries convey blood to the section  [...]

MSUD or maple syrup urine disease is a condition that has the potential to cause grave consequences due the manner in which it impinges on the body’s capacity of breaking down three kinds of amino acids namely leucine, isoleucine and valine. The three amino acids when not employed for building protein go through the process of recycling, breaking down and utilised for energy. BCKD or branched-chain alpha-ketoacid dehydrogenase is the team formed by the unison of six proteins that generally break down the three amino acids. Individuals having MSUD possess a mutation that leads to a paucity of one of the six proteins which constitute the BCKD complex. Hence, their bodies are incapable of breaking down the three amino acids present in their blood stream leading to brisk deterioration of brain  [...]